Injection or injection means introducing a liquid into the body with a hypodermic needle --
One quick injection and you'll be safe from the flu for another year.
He'll become drowsy a few minutes after the injection.
Injection may also mean the introduction of something new or unexpected, figuratively --
He hoped that an injection of humor might save the situation.
Interjection or interjection means an emotional outburst or remark, or a word used alone, to express emotion, that doesn't otherwise alter the meaning of what is said or written --
His every sentence is preceded by an unprintable interjection.
That interjection seems out of character; our heroine wouldn't say "OMG!"
Now that you know that, you can say --
"He's had an injection of painkillers, and now his only words are the interjection "uh-oh".
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