Delirious or delirious means raving or deranged --
He's delirious; I think he hit his head.
His parents think he has been taking drugs; he was delirious when he came home last night.
Deleterious or deleterious describes something that causes or results in harm of some kind --
Lack of exercise can have a deleterious effect on your health.
His new friends are a deleterious influence.
Now that you know that, you can say --
"This new medication can have deleterious side effects, and it may render the patient delirious."
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