nowhere, know where

Nowhere or nowhere means not any place; a pretend or non-existent place or state, or, figuratively,  a state of anonymity or obscurity, or of failure to move ahead or succeed--
"He's a real nowhere man, sitting in his nowhere land..."
We looked everywhere; the tickets are nowhere to be found.
He was thirty, and getting nowhere .
This argument is getting us nowhere.

Know where or know where means to have knowledge or perception as to the location of some place or thing--
"Do you know where you're going to?"
He doesn't know where he left his keys.

Now that you know that, you can say--
"If you don't know where you lost them, all this searching will get us nowhere."

Note--"no, where?" is a negative response to a question concerning the location of a place or thing--
Do you know where we're going on Saturday?
No, where?