Psychosis or psychosis means a serious mental disorder--
The doctor says his psychosis can be treated with psychotherapy.
He has been hospitalized for drug-induced psychosis.
Sycosis or sycosis ( rhymes with psychosis ) means a skin disease or disorder; an inflammation of the hair follicles--
The doctor prescribed a medicine for his sycosis that seems to be working.
He has sycosis, and wants to stay at home until it looks better.
Now that you know that, you can say--
"The doctor thought his ailment was imaginary, and a product of psychosis, but he had a severe case of sycosis, that cleared up with treatment."
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