Desperate or desperate means having a great need or desire--
He might have done it. He is desperate for money.
Desperate times call for desperate measures.
Desperate may mean showing a reckless disregard for consequences or safety--
He drove to the hospital in desperate haste.
Desperate may mean having no hope, or in despair--
He made a desperate effort to get into the burning building, before the flames drove him back.
It was a sordid tale of the desperate enterprises of desperate men.
Disparate or disparate means of markedly different kinds, or essentially unlike--
We need a marketing campaign that will promote all of our disparate enterprises.
The two diseases have similar symptoms, but disparate causes.
Now that you know that, you can say--
"The doctor tried varied and disparate treatments before resorting to the desperate, life-threatening procedure."
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